Supplements

Evidence-Based Supplements

Science-backed information on supplements for weight loss, metabolic health, and overall wellness.

8 Articles

Supplements12 min

Creatine on GLP-1 Medications: Does It Preserve Muscle?

Creatine is the most-recommended supplement for muscle loss on semaglutide and tirzepatide. Here is what the trials actually prove — and what they do not.

Metabolic Science Editorial

Supplements7 min

Weight-Loss Supplements: Evidence, Benefits and Risks

Do weight-loss supplements work? Compare berberine, green tea extract and fiber, understand safety risks, and check evidence and labels before buying.

Metabolic Science Editorial

Supplements9 min

Natural GLP-1 Boosters: Foods, Supplements & Habits

Discover evidence-based foods, supplements, and lifestyle habits that naturally increase GLP-1 secretion to improve glucose control, reduce appetite, and support weight loss.

Metabolic Science Editorial

Supplements9 min

Natural Thermogenic Supplements: Weight Loss and Safety

Do natural thermogenics help with weight loss? Compare capsaicin, green tea, ginger, bitter orange and berberine, including evidence limits and safety concerns.

Metabolic Science Editorial

Supplements9 min

Protein Powder for Weight Loss and Muscle Preservation: A Complete Guide

Everything you need to know about protein powder supplements — types, benefits for weight loss and muscle preservation, optimal dosing, and how to choose the right product.

Metabolic Science Editorial

Supplements8 min

Fiber Supplements for Weight Loss: Types, Benefits, and Evidence

Learn how fiber supplements support weight loss through satiety, blood sugar control, and gut health. Compare soluble vs. insoluble fiber and find the right type for your goals.

Metabolic Science Editorial

Supplements8 min

Probiotics and Weight Loss: Can Gut Bacteria Influence Your Weight?

Explore the emerging science behind probiotics and weight management — which strains show promise, what the research actually says, and how gut health connects to metabolism.

Metabolic Science Editorial

Supplements9 min

Berberine for Weight Loss and Blood Sugar: What Does the Evidence Say?

A comprehensive, evidence-based review of berberine — how it works, its effects on blood sugar, weight, and cholesterol, dosing, side effects, and how it compares to metformin.

Metabolic Science Editorial