Prescription Weight Loss Drugs
Evidence-based guides on prescription weight loss medications — dosing, comparisons, insurance coverage, injection technique, and what to expect when starting therapy.
16 Articles
Generic Semaglutide 2026: Where It's Available and What It Costs
Generic semaglutide reached India, Canada, and Brazil in 2026 at up to 90% off brand prices. What it costs, whether it works the same, and when the US gets it.
Metabolic Science Editorial
What to Eat on GLP-1 Medications: A Nutrition Guide
What to eat on GLP-1 medications matters more than most people realize. A science-based guide to protein targets, fiber, hydration, and managing side effects.
Metabolic Science Editorial
GLP-1 Medications and Nutrient Deficiencies: What to Monitor
GLP-1 drugs cut appetite so sharply that many users fall short on protein, vitamin D, iron, and B12. Learn what the research shows and how to monitor nutrient status.
Metabolic Science Editorial
Setmelanotide (Imcivree): The MC4R Drug for Genetic Obesity
Setmelanotide (Imcivree) is the MC4R agonist for rare genetic and acquired hypothalamic obesity. Here's how it works, who it helps, and the trial data.
Metabolic Science Editorial
Microdosing GLP-1 Medications: Does It Work for Weight Loss?
Microdosing GLP-1 drugs like semaglutide and tirzepatide is trending, but what does the science say? We break down the dose-response evidence, the maintenance question, and the real risks.
Metabolic Science Editorial
Compounded Semaglutide: Safety, Efficacy, and What the FDA Says
Is compounded semaglutide safe and effective? A clinical review of FDA warnings, 1,150+ adverse events, regulatory changes, and what patients need to know before using compounded GLP-1 drugs.
Metabolic Science Editorial
Mounjaro Dosage Chart: Dose Steps and Missed-Dose Rules
Mounjaro dose strengths, escalation intervals and missed-dose rules from the current US label, with separate adult and pediatric limits.
Metabolic Science Editorial
Plenity for Weight Loss: How It Works, Efficacy & Side Effects
A comprehensive guide to Plenity (Gelesis100), the FDA-cleared oral hydrogel for weight management. Learn about efficacy data, how it works, and who qualifies.
Metabolic Science Editorial
Qsymia vs GLP-1 Medications: A Head-to-Head Comparison
How does Qsymia (phentermine/topiramate ER) compare to semaglutide and tirzepatide? Evidence-based breakdown of efficacy, safety, cost, and who each medication suits best.
Metabolic Science Editorial
Contrave Review: Efficacy, Side Effects, and Who Should Consider It
A comprehensive, evidence-based review of Contrave (naltrexone/bupropion) for weight loss: how it works, clinical trial results, side effects, and how it compares to GLP-1 medications.
Metabolic Science Editorial
GLP-1 Storage: Mounjaro, Ozempic, Wegovy and Zepbound
Compare US storage instructions by brand and device, including room-temperature limits, in-use periods and what to check after a temperature excursion.
Metabolic Science Editorial
GLP-1 Injection Technique: A Complete Step-by-Step Guide
Master GLP-1 injection technique with evidence-based guidance on sites, needle selection, rotation, and managing injection-site reactions for optimal outcomes.
Metabolic Science Editorial
Insurance Coverage for Weight Loss Drugs: A Complete Guide
Navigate insurance coverage for GLP-1 medications like Wegovy and Zepbound. Learn what Medicare, Medicaid, and private plans cover—plus strategies to reduce your out-of-pocket costs.
Metabolic Science Editorial
Mounjaro vs Ozempic: Brands, Devices and Access
A practical checklist for comparing Mounjaro and Ozempic with your clinician: exact product, device, coverage, follow-up and questions before switching.
Metabolic Science Editorial
Starting GLP-1: What to Expect in Your First Months
A complete guide to starting GLP-1 medications. Learn what to expect week-by-week, how to manage side effects, injection techniques, and realistic weight loss timelines from clinical trials.
Metabolic Science Editorial
How GLP-1 Medications Work: The Science Behind Weight Loss Drugs
Understand the mechanisms of GLP-1 receptor agonists like semaglutide and tirzepatide. Learn how these medications promote weight loss through appetite suppression, delayed gastric emptying, and metabolic effects.
Metabolic Science Editorial